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Article

Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization.

The EMBO journal - 8 Mar 2006

Liu Han, Deng Xuehong, Shyu Y John, Li Jian Jian, Taparowsky Elizabeth J, Hu Chang-Deng

Abstract excerpt

ATF2 and c-Jun are key components of activating protein-1 and function as homodimers or heterodimers. c-Jun-ATF2 heterodimers activate the expression of many target genes, including c-jun, in response to a variety of cellular and environmental signals. Although it has been believed that c-Jun and ATF2 are constitutively localized in the nucleus, where they are phosphorylated and activated by mitogen-activated...

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Source

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Identifiers

PMID: 16511568
DOI: 10.1038/sj.emboj.7601020
PMCID: PMC1409714

Genes

ATF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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