Article
Importins and exportins regulating allergic immune responses.
Mediators of inflammation - 1 Jan 2014
Aggarwal Ankita, Agrawal Devendra K
Abstract excerpt
Nucleocytoplasmic shuttling of macromolecules is a well-controlled process involving importins and exportins. These karyopherins recognize and bind to receptor-mediated intracellular signals through specific signal sequences that are present on cargo proteins and transport into and out of the nucleus through nuclear pore complexes. Nuclear localization signals (NLS) present on cargo molecules to be imported while...
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