Article
Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
Psychopharmacology - 1 Nov 2007
Palucha Agnieszka, Klak Kinga, Branski Piotr, van der Putten Herman, Flor Peter J, Pilc Andrzej
Abstract excerpt
RATIONALE: Broad evidence indicates that modulation of the glutamatergic system could be an efficient way to achieve antidepressant activity. Metabotropic glutamate receptor (mGlu receptor) ligands seem to be promising agents to treat several central nervous system disorders, including psychiatric ones. OBJECTIVES: The aim of our study was to investigate potential antidepressant-like activity of the first,...
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