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Article

Association study of the serotonin transporter promoter polymorphism and mirtazapine antidepressant response in major depressive disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 15 Aug 2007

Kang Rhee-Hun, Wong Ma-Li, Choi Myoung-Jin, Paik Jong-Woo, Lee Min-Soo

Abstract excerpt

Modulations of serotonergic and noradrenergic systems are thought to be critical to the therapeutic effect of most antidepressants, and their efficacies have been shown to depend on a functional polymorphism within the promoter region of the serotonin transporter gene (5-HTTLPR). Mirtazapine has a dual-action profile, combining the enhancement of the noradrenergic neurotransmitter system with specific actions on...

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Identifiers

PMID: 17618721
DOI: 10.1016/j.pnpbp.2007.05.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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