Article
Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2005
Yu Younger W-Y, Tsai Shih-Jen, Hong Chen-Jee, Chen Tai-Jui, Chen Ming-Chao, Yang Chih-Wei
Abstract excerpt
Monoamine oxidase A (MAOA), a mitochondrial enzyme involved in the degradation of biogenic amines, may be implicated in the pathogenesis of major depressive disorder (MDD) and be related to the therapeutic effects of antidepressants. To elucidate a genetic predisposition of MDD, we studied a variable-number-tandem-repeat (VNTR) polymorphism in the promoter region of the MAOA gene in a Chinese population of 230...
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