Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression.

Archives of general psychiatry - 1 Nov 2004

Murphy Greer M, Hollander Steven B, Rodrigues Heidi E, Kremer Charlotte, Schatzberg Alan F

Abstract excerpt

BACKGROUND: The "long/short"polymorphism (5HTTLPR) in the promoter of the serotonin transporter gene (SLC6A4) has been proposed as a pharmacogenetic marker for antidepressant efficacy. Some but not all studies have found that the short form of 5HTTLPR (S allele) results in decreased efficacy of s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ambulatory Care
Share to Depressive Disorder, Major
Share to Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Paroxetine

Share to Pharmacogenetics

Share to Proportional Hazards Models

Share to Selective Serotonin Reuptake Inhibitors

Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 15520364
DOI: 10.1001/archpsyc.61.11.1163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15520364-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression.PMID 15520364Read ↗

Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients.Semantic proximity Read ↗

Pharmacogenetics and the serotonin transporter in late-life depressionSemantic proximity Read ↗

Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment.Semantic proximity Read ↗

Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression.Semantic proximity Read ↗

Antidepressant response and the serotonin transporter gene-linked polymorphic region.Semantic proximity Read ↗

The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder.Semantic proximity Read ↗

Serotonin Transporter Gene Polymorphisms and Selective Serotonin Reuptake Inhibitor Tolerability: Review of Pharmacogenetic EvidenceSemantic proximity Read ↗

The influence of 5-HTTLPR genotype on the association between the plasma concentration and therapeutic effect of paroxetine in patients with major depressive disorder.Semantic proximity Read ↗

5-HTTLPR modulates antidepressant efficacy in depressed women.Semantic proximity Read ↗

Pharmacogenetics of selective serotonin reuptake inhibitors (SSRI): A serotonin reuptake transporter (SERT)-based approach.Semantic proximity Read ↗

Serotonin transporter (5-HTT) promoter genotype may influence the prolactin response to clomipramine.Semantic proximity Read ↗

Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.