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Article

Serotonin transporter gene polymorphisms and sertraline response in major depression patients.

Genetic testing - 1 Jun 2008

Dogan Ozlem, Yuksel Nevzat, Ergun Mehmet Ali, Yilmaz Akin, Ilhan Mustafa N, Karslioglu Hatice Ersin, Koc Aysegul, Menevse Adnan

Abstract excerpt

Major depression (MD) has a complex multifactorial etiology with genetic and environmental factors contributing to the disorder. As with all antidepressant treatments, there is variability in drug response due to heredity, generally focusing on genetic polymorphism of the drug-metabolizing transporter genes. The serotonin transporter (5-HTT) gene is a particularly important candidate for genetic involvement in MD...

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Source

Identifiers

PMID: 18452396
DOI: 10.1089/gte.2007.0089

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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