Article
Serotonin transporter gene polymorphism and antidepressant response.
Neuroreport - 17 Jan 2000
Kim D K, Lim S W, Lee S, Sohn S E, Kim S, Hahn C G, Carroll B J
Abstract excerpt
We examined allelic polymorphisms of the serotonin transporter (5-HTT) gene and antidepressant response to 6 weeks' treatment with the selective serotonin reuptake inhibitor (SSRI) drugs fluoxetine or paroxetine. We genotyped 120 patients and 252 normal controls, using polymerase chain reaction of genomic DNA with primers flanking the second intron and promoter regions of the 5-HTT gene. Diagnosis of depression...
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