Article
Is 5-HTTLPR linked to the response of selective serotonin reuptake inhibitors in MDD?
European archives of psychiatry and clinical neuroscience - 1 Mar 2011
Illi Ari, Poutanen Outi, Setälä-Soikkeli Eija, Kampman Olli, Viikki Merja, Huhtala Heini, Mononen Nina, Haraldsson Susann, Koivisto Pasi A, Leinonen Esa, Lehtimäki Terho
Abstract excerpt
The role of a functional polymorphism in the transcriptional control region of serotonin transporter gene (5-HTTLPR, SERTPR) has been studied intensively in major depression and in the response to selective serotonin inhibitors (SSRIs) in major depression. The findings have been contradictory, although majority of the studies indicate that the short allele is associated with poor response to SSRIs in major...
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