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Article

CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer.

Journal of cancer research and clinical oncology - 1 Jan 2008

Boccia Stefania, Cadoni Gabriella, Sayed-Tabatabaei Fakhredin A, Volante Mariangela, Arzani Dario, De Lauretis Angelo, Cattel Caterina, Almadori Giovanni, van Duijn Cornelia M, Paludetti Gaetano, Ricciardi Gualtiero

Abstract excerpt

PURPOSE: As risk-modifiers of alcohol and tobacco effects, metabolic genes polymorphisms were investigated as susceptibility candidates for squamous cell carcinoma of the head and neck (SCCHN). METHODS: A total of 210 cases and 245 hospital controls, age and gender matched, were genotyped for CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms. A measurement of the biological interaction...

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Source

Identifiers

PMID: 17611777
DOI: 10.1007/s00432-007-0254-5

Genes

EPHX1
GSTM1
GSTT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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