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Article

Combined effect of smoking and polymorphisms in tobacco carcinogen-metabolizing enzymes CYP1A1 and GSTM1 on the head and neck cancer risk in North Indians.

DNA and cell biology - 1 Aug 2010

Sharma Rajni, Ahuja Monica, Panda Naresh K, Khullar Madhu

Abstract excerpt

Tobacco consumption contributes to the etiology of majority of cancers, and polymorphisms in tobacco-metabolizing enzymes may modulate susceptibility to head and neck cancer (HNC). The aim of this study was to determine whether genetic polymorphisms in genes CYP1A1 and GSTM1, involved in metabolism of major classes of tobacco-derived carcinogens, may predispose to development of HNC in a North Indian population....

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Source

Identifiers

PMID: 20491576
DOI: 10.1089/dna.2009.1016

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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