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Influence of the CYP1A1 T3801C Polymorphism on Tobacco and Alcohol-Associated Head and Neck Cancer Susceptibility in Northeast India.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Singh Seram Anil, Choudhury Javed Hussain, Kapfo Wetetsho, Kundu Sharbadeb, Dhar Bishal, Laskar Shaheen, Das Raima, Kumar Manish, Ghosh Sankar Kumar

Abstract excerpt

BACKGROUND: Tobacco and alcohol contain or may generate carcinogenic compounds related to cancers. CYP1A1 enzymes act upon these carcinogens before elimination from the body. The aim of this study was to investigate whether CYP1A1 T3801C polymorphism modulates the relationship between tobacco and alcohol- associated head and neck cancer (HNC) susceptibility among the northeast Indian population. MATERIALS AND...

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Alcohol Drinking
Areca
Cytochrome P-450 CYP1A1
Gene-Environment Interaction
Head and Neck Neoplasms

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Multifactor Dimensionality Reduction

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PMID: 26514474
DOI: 10.7314/apjcp.2015.16.16.6953

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