Article
Interaction of glutathione-s-transferase genotypes with environmental risk factors in determining susceptibility to head and neck cancer and treatment response and survival outcome.
Environmental and molecular mutagenesis - 1 Jun 2020
Katiyar Tridiv, Yadav Vinay, Maurya Shailendra S, Ruwali Munindra, Singh Madhu, Hasan Feza, Pandey Rahul, Mehrotra Divya, Singh Sudhir, Mishra Shambhavi, Hadi Rahat, Bhatt Madan L B, Parmar Devendra
Abstract excerpt
The present case-control study aimed to investigate the role of interaction of glutathione-s-transferase (GST) genotypes with environmental risk factors in determining susceptibility to head and neck squamous cell carcinoma (HNSCC) involving 1,250 cases and equal number of healthy controls. An increase in the risk of HNSCC and its subsites (larynx, pharynx, and oral cavity) was observed among the cases with null...
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