Article
Gene-environment interaction and susceptibility in head and neck cancer patients and in their first-degree relatives: a study of Northeast Indian population.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Aug 2015
Choudhury Javed Hussain, Ghosh Sankar Kumar
Abstract excerpt
BACKGROUND: The environmental and genetic factors are known to be associated with head and neck squamous cell carcinoma (HNSCC). Here, we investigated the GSTM1 and GSTT1 polymorphisms and tobacco uses in patients and in their first-degree relatives to evaluate susceptibility toward HNSCC. Further, we explored high-risk interaction between genetic and environmental risk factors. SUBJECTS AND METHODS: Genotyping...
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