Tobacco carcinogen-metabolizing genes CYP1A1, GSTM1, and GSTT1 polymorphisms and their interaction with tobacco exposure influence the risk of head and neck cancer in Northeast Indian population.

doi:10.1007/s13277-015-3246-0

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Article

Tobacco carcinogen-metabolizing genes CYP1A1, GSTM1, and GSTT1 polymorphisms and their interaction with tobacco exposure influence the risk of head and neck cancer in Northeast Indian population.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2015

Choudhury Javed Hussain, Singh Seram Anil, Kundu Sharbadeb, Choudhury Biswadeep, Talukdar Fazlur R, Srivasta Shilpee, Laskar Ruhina S, Dhar Bishal, Das Raima, Laskar Shaheen, Kumar Manish, Kapfo Wetetsho, Mondal Rosy, Ghosh Sankar Kumar

Abstract excerpt

Genetic polymorphisms in tobacco-metabolizing genes may modulate the risk of head and neck cancer (HNC). In Northeast India, head and neck cancers and tobacco consumption remains most prevalent. The aim of the study was to investigate the combined effect of cytochrome P450 1A1 (CYP1A1) T3801C, glutathione S-transferases (GSTs) genes polymorphisms and smoking and tobacco-betel quid chewing in the risk of HNC. The...

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PMID: 25724184
DOI: 10.1007/s13277-015-3246-0

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GSTM1
GSTT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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