Article
Risk of head and neck cancer and the alcohol dehydrogenase 3 genotype.
Carcinogenesis - 1 Jan 2001
Olshan A F, Weissler M C, Watson M A, Bell D A
Abstract excerpt
Squamous cell carcinoma of the head and neck (SCCHN), including the oral cavity, pharynx and larynx, is an excellent tumor model to evaluate gene-environment interactions, including alcohol and alcohol-metabolizing enzymes such as alcohol dehydrogenase (ADH). We conducted a hospital-based case-control study including 182 cases with newly diagnosed SCCHN and 202 controls with non-neoplastic conditions of the head...
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