Article
Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population.
BMC cancer - 8 Nov 2007
Boccia Stefania, Sayed-Tabatabaei Fakhredin A, Persiani Roberto, Gianfagna Francesco, Rausei Stefano, Arzani Dario, La Greca Antonio, D'Ugo Domenico, La Torre Giuseppe, van Duijn Cornelia M, Ricciardi Gualtiero
Abstract excerpt
BACKGROUND: The distribution and the potential gene-gene and gene-environment interaction of selected metabolic genetic polymorphisms was investigated in relation to gastric cancer risk in an Italian population. METHODS: One hundred and seven cases and 254 hospital controls, matched by age and gender, were genotyped for CYP1A1, CYP2E1, mEH, GSTM1, GSTT1, NAT2 and SULT1A1 polymorphisms. Haplotype analysis was...
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