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Article

Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies.

BMC genomics - 4 Jul 2007

Docherty Sophia J, Butcher Lee M, Schalkwyk Leonard C, Plomin Robert

Abstract excerpt

BACKGROUND: Genetic influences underpinning complex traits are thought to involve multiple quantitative trait loci (QTLs) of small effect size. Detection of such QTL associations requires systematic screening of large numbers of DNA markers within large sample populations. Using pooled DNA on SNP microarrays to screen for allelic frequency differences between groups such as cases and controls (called SNP...

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Identifiers

PMID: 17610740
DOI: 10.1186/1471-2164-8-214
PMCID: PMC1925094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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