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A comparison of DNA pools constructed following whole genome amplification for two-stage SNP genotyping designs.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Aug 2005

Zhao Zhen Zhen, Nyholt Dale R, James Michael R, Mayne Renee, Treloar Susan A, Montgomery Grant W

Abstract excerpt

Genotyping in DNA pools reduces the cost and the time required to complete large genotyping projects. The aim of the present study was to evaluate pooling as part of a strategy for fine mapping in regions of significant linkage. Thirty-nine single nucleotide polymorphisms (SNPs) were analyzed in two genomic DNA pools of 384 individuals each and results compared with data after typing all individuals used in the...

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PMID: 16176720
DOI: 10.1375/1832427054936718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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