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Article

Microarray-based genome-wide association studies using pooled DNA.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Szelinger Szabolcs, Pearson John V, Craig David W

Abstract excerpt

Pooling genomic DNA samples within clinical classes of disease for use in whole-genome single nucleotide polymorphism (SNP) genotyping allows for rapid and inexpensive genome-wide association studies (GWAS). We describe here a general outline for combining hundreds of genomic DNA samples prior to genotyping on commercially available high-density SNP microarrays. The pool construction approach is universal, and...

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PMID: 21204026
DOI: 10.1007/978-1-61737-954-3_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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