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Article

Highly cost-efficient genome-wide association studies using DNA pools and dense SNP arrays.

Nucleic acids research - 1 Apr 2008

Macgregor Stuart, Zhao Zhen Zhen, Henders Anjali, Nicholas Martin G, Montgomery Grant W, Visscher Peter M

Abstract excerpt

Genome-wide association (GWA) studies to map genes for complex traits are powerful yet costly. DNA-pooling strategies have the potential to dramatically reduce the cost of GWA studies. Pooling using Affymetrix arrays has been proposed and used but the efficiency of these arrays has not been quantified. We compared and contrasted Affymetrix Genechip HindIII and Illumina HumanHap300 arrays on the same DNA pools and...

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Identifiers

PMID: 18276640
DOI: 10.1093/nar/gkm1060
PMCID: PMC2346606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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