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Article

Pooled DNA genotyping on Affymetrix SNP genotyping arrays.

BMC genomics - 15 Feb 2006

Kirov George, Nikolov Ivan, Georgieva Lyudmila, Moskvina Valentina, Owen Michael J, O'Donovan Michael C

Abstract excerpt

BACKGROUND: Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high. Pooled DNA genotyping offers the possibility of applying the same technologies at a fraction of the cost, and there is some evidence that certain ultra-high throughput platforms also perform with an...

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PMID: 16480507
DOI: 10.1186/1471-2164-7-27
PMCID: PMC1382214

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