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The SNPMaP package for R: a framework for genome-wide association using DNA pooling on microarrays.

Bioinformatics (Oxford, England) - 15 Jan 2009

Davis Oliver S P, Plomin Robert, Schalkwyk Leonard C

Abstract excerpt

SUMMARY: Large-scale genome-wide association (GWA) studies using thousands of high-density SNP microarrays are becoming an essential tool in the search for loci related to heritable variation in many phenotypes. However, the cost of GWA remains beyond the reach of many researchers. Fortunately, the majority of statistical power can still be obtained by estimating allele frequencies from DNA pools, reducing the...

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PMID: 19008252
DOI: 10.1093/bioinformatics/btn587
PMCID: PMC2639010

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CEL

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