Article
Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans.
Nucleic acids research - 14 Feb 2006
Meaburn Emma, Butcher Lee M, Schalkwyk Leonard C, Plomin Robert
Abstract excerpt
The identification of quantitative trait loci (QTLs) of small effect size that underlie complex traits poses a particular challenge for geneticists due to the large sample sizes and large numbers of genetic markers required for genomewide association scans. An efficient solution for screening purposes is to combine single nucleotide polymorphism (SNP) microarrays and DNA pooling (SNP-MaP), an approach that has...
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