Article
Allelotyping of pooled DNA with 250 K SNP microarrays.
BMC genomics - 16 Mar 2007
Wilkening Stefan, Chen Bowang, Wirtenberger Michael, Burwinkel Barbara, Försti Asta, Hemminki Kari, Canzian Federico
Abstract excerpt
BACKGROUND: Genotyping technologies for whole genome association studies are now available. To perform such studies to an affordable price, pooled DNA can be used. Recent studies have shown that GeneChip Human Mapping 10 K and 50 K arrays are suitable for the estimation of the allele frequency in pooled DNA. In the present study, we tested the accuracy of the 250 K Nsp array, which is part of the 500 K array set...
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