Article
The epidermal growth factor receptor intron1 (CA) n microsatellite polymorphism is a potential predictor of treatment outcome in patients with advanced lung cancer treated with Gefitinib.
European journal of pharmacology - 10 Sept 2007
Nie Qiang, Wang Zhen, Zhang Guo-Chun, An She-Juan, Lin Jia-Yin, Guo Ai-Lin, Li Rong, Gan Bin, Huang Ying, Mok Tony S, Wu Yi-Long
Abstract excerpt
The goal of our study was to assess the association between R497K and intron1 (CA) n repeat genetic polymorphisms of the EGF (epidermal growth factor) receptor and the clinical outcome of patients with advanced non-small cell lung cancer treated with EGF receptor tyrosine kinase inhibitor. We determined the genotypes for R497K and intron1 (CA) n repeat genetic polymorphisms of 70 Chinese patients with advanced...
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