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Article

Genetic polymorphism in the epidermal growth factor receptor gene predicts outcome in advanced non-small cell lung cancer patients treated with erlotinib.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2015

Winther-Larsen Anne, Nissen Peter Henrik, Jakobsen Kristine Raaby, Demuth Christina, Sorensen Boe Sandahl, Meldgaard Peter

Abstract excerpt

OBJECTIVES: Epidermal growth factor receptor (EGFR) mutations are important predictors of treatment response to tyrosine kinase inhibitors (TKIs) in patients with non-small cell lung cancer (NSCLC). However, some patients with mutations do not respond and some patients without mutations show response. We therefore need additional biomarkers to improve the selection of these patients for treatment. A promising...

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Source

Identifiers

PMID: 26386832
DOI: 10.1016/j.lungcan.2015.09.003

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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