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Article

An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors.

Cancer research - 15 Dec 2004

Amador Maria L, Oppenheimer Darin, Perea Sofia, Maitra Anirban, Cusatis George, Cusati George, Iacobuzio-Donahue Christi, Baker Sharyn D, Ashfaq Raheela, Takimoto Chris, Forastiere Arlene, Hidalgo Manuel

Abstract excerpt

This study tested the hypothesis that the number of CA single sequence repeat (CA-SSR) in the intron 1 of the epidermal growth factor receptor (egfr) gene, which affects transcription efficiency of the gene, is associated with the response to EGFR inhibitors. To this end, we determined the number...

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Source

Identifiers

PMID: 15604284
DOI: 10.1158/0008-5472.CAN-04-1036

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15604284-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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