Article
Association of the EGFR intron 1 CA repeat length with lung cancer risk.
Molecular carcinogenesis - 1 May 2007
Zhang Weiping, Weissfeld Joel L, Romkes Marjorie, Land Stephanie R, Grandis Jennifer R, Siegfried Jill M
Abstract excerpt
Epidermal growth factor receptor (EGFR) plays an important role in the development and progression of lung cancer. A previous report noted that an increased number of polymorphic CA repeats in the first intron of the EGFR gene results in decreased transcriptional activity. To estimate the association of the length of polymorphic CA repeats in intron 1 of the EGFR gene with lung cancer, a case-control study of 176...
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