Article
Lack of evidence for prognostic value of epidermal growth factor receptor intron-1 CA repeats for oral carcinomas.
European journal of oral sciences - 1 Apr 2017
Precht Clarissa, Blessmann Marco, Kluwe Lan, Scheld Theresa, Schön Gerhard, Henningsen Anders, Pflug Christina, Smeets Ralf, Heiland Max, Gröbe Alexander
Abstract excerpt
Epidermal growth factor receptor (EGFR) expression is altered in several malignancies, including oral squamous cell carcinoma. A CA-repeat polymorphism in intron-1 (CA-SSR-1) of the EGFR gene is reported to influence EGFR expression and is associated with features of various solid tumors and outcomes of cancer patients. In the present study we evaluated the influence of length and zygosity of CA-SSR-1 on the...
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