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Article

Polymorphisms of EGFR predict clinical outcome in advanced non-small-cell lung cancer patients treated with Gefitinib.

Lung cancer (Amsterdam, Netherlands) - 1 Oct 2009

Ma Fei, Sun Tong, Shi Yuankai, Yu Dianke, Tan Wen, Yang Ming, Wu Chen, Chu Datong, Sun Yan, Xu Binghe, Lin Dongxin

Abstract excerpt

PURPOSE: Genetic variations in EGFR may alter protein function and therefore the therapeutic efficacy of epidermal growth factor receptor inhibitors. This study investigated the association between polymorphisms in EGFR and clinical outcome in patients with advanced non-small-cell lung cancer (NS...

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Source

Identifiers

PMID: 19201048
DOI: 10.1016/j.lungcan.2008.12.025

Genes

EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19201048-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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