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Article

No association between dinucleotide repeat polymorphism in intron 1 of the epidermal growth factor receptor gene EGFR and risk of lung cancer.

Cancer genetics and cytogenetics - 1 Jan 2007

Lee Su Jeong, Kim Kyung Mee, Chae Myung Hwa, Lee Won Kee, Kam Sin, Cha Sung Ick, Han Hyung Soo, Kim Chang Ho, Kang Young Mo, Han Sung Beom, Park Jae Yong

Abstract excerpt

The tyrosine kinase receptor EGFR pathway is one of the oncogenic signaling cascades involved in lung cancer, mediating the epidermal growth factor receptor gene EGFR. First-intron polymorphisms with greater numbers of CA dinucleotide repeats tend to downregulate EGFR expression, which suggests that this polymorphism may modulate susceptibility to lung cancer. The present hospital-based case-control study...

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PMID: 17175376
DOI: 10.1016/j.cancergencyto.2006.07.012

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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