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Article

The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion.

Kidney international - 1 Sept 2007

Rieg T, Vallon V, Sausbier M, Sausbier U, Kaissling B, Ruth P, Osswald H

Abstract excerpt

The kidney is the major regulator of potassium homeostasis. In addition to the ROMK channels, large conductance Ca(2+)-activated K(+) (BK) channels are expressed in the apical membrane of the aldosterone sensitive distal nephron where they could contribute to renal K(+) secretion. We studied flow-induced K(+) secretion in BK channel alpha-subunit knockout (BK(-/-)) mice by acute pharmacologic blockade of...

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Identifiers

PMID: 17579662
DOI: 10.1038/sj.ki.5002369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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