Article

Increased severity of chronic kidney disease in response to high potassium intake is dependent on mineralocorticoid receptor activation

2022-06-17

Abstract excerpt

Dietary treatment is seminal for management of chronic kidney disease (CKD). The aim of our project was to assess the effects of potassium intake on the progression of CKD. We used 2 mouse CKD models to analyze the effects of potassium intake on CKD : the unilateral ureteral obstruction (UUO) and the POD-ATTAC models. POD-ATTAC mice display a podocyte-specific apoptosis after the administration of a chemical induc...

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Literature Corpus work: feb33347-a44f-5b53-be06-f352f7a4b986
DOI: 10.1101/2022.06.15.496280

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