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Article

Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2.

The Journal of biological chemistry - 3 Aug 2007

Singh Minati, Kesterson Robert A, Jacobs Michelle M, Joers James M, Gore John C, Emeson Ronald B

Abstract excerpt

ADAR2 is a double-stranded RNA-specific adenosine deaminase involved in the editing of mammalian RNAs by the site-specific conversion of adenosine to inosine. To examine the physiologic consequences resulting from ADAR2 misexpression, we have generated mutant mice expressing either wild-type or deaminase-deficient ADAR2 transgenes under the control of the human cytomegalovirus promoter. Transgenic mice expressing...

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Source

Identifiers

PMID: 17567573
DOI: 10.1074/jbc.M700265200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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