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Article

High fat diet rescues disturbances to metabolic homeostasis and survival in the Id2 null mouse in a sex-specific manner.

Biochemical and biophysical research communications - 29 Aug 2014

Zhou Peng, Hummel Alyssa D, Pywell Cameron M, Dong X Charlie, Charlie Dong X, Duffield Giles E

Abstract excerpt

Inhibitor of DNA binding 2 (ID2) is a helix-loop-helix transcriptional repressor rhythmically expressed in many adult tissues. Our previous studies have demonstrated that Id2 null mice have altered expression of circadian genes involved in lipid metabolism, altered circadian feeding behavior, and sex-specific enhancement of insulin sensitivity and elevated glucose uptake in skeletal muscle and brown adipose...

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Identifiers

PMID: 25108156
DOI: 10.1016/j.bbrc.2014.07.106
PMCID: PMC4262528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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