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Article

Structure and sequence determinants required for the RNA editing of ADAR2 substrates.

The Journal of biological chemistry - 6 Feb 2004

Dawson T Renee, Sansam Christopher L, Emeson Ronald B

Abstract excerpt

ADAR2 is a double-stranded RNA-specific adenosine deaminase involved in the editing of mammalian RNAs by the site-specific conversion of adenosine to inosine. We have demonstrated previously that ADAR2 can modify its own pre-mRNA, leading to the creation of a proximal 3'-splice junction containing a non-canonical adenosine-inosine (A-I) dinucleotide. Alternative splicing to this proximal acceptor shifts the...

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Source

Identifiers

PMID: 14660658
DOI: 10.1074/jbc.M310068200

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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