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Article

Affect-related behaviors in mice misexpressing the RNA editing enzyme ADAR2.

Physiology & behavior - 22 Jun 2009

Singh Minati, Zimmerman M Bridget, Beltz Terry G, Johnson Alan Kim

Abstract excerpt

Misediting of the serotonin (5HT) 2C receptor (5HT(2C)R) has been implicated in both depression and anxiety. The adenosine deaminases that act on double stranded RNAs (ADARs) are reported to modify the 5HT(2C)R by RNA editing. Transgenic mice misexpressing the RNA editing enzyme ADAR2 show an adult onset obese phenotype due to chronic hyperphagia, but little more than this is known about the behavior of these...

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Source

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Identifiers

PMID: 19361536
DOI: 10.1016/j.physbeh.2009.03.029
PMCID: PMC2778280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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