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Article

The IRF5 polymorphism in type 1 diabetes.

Journal of medical genetics - 1 Oct 2007

Qu Hui-Qi, Marchand Luc, Grabs Rosemary, Polychronakos Constantin

Abstract excerpt

The interferon regulatory factor 5 gene (IRF5) has been shown to play a crucial role in harmful immune responses by induction of proinflammatory cytokines. Functional genetic variants associated with increased IRF5 expression of specific isoforms are associated with systemic lupus erythematosus (SLE) and it is possible that they may also predispose to other autoimmune disorders. We tested the association of two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17557928
DOI: 10.1136/jmg.2007.050971
PMCID: PMC2597969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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