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Article

Opposed independent effects and epistasis in the complex association of IRF5 to SLE.

Genes and immunity - 1 Jul 2007

Ferreiro-Neira I, Calaza M, Alonso-Perez E, Marchini M, Scorza R, Sebastiani G D, Blanco F J, Rego I, Pullmann R, Pullmann R, Kallenberg C G, Bijl M, Skopouli F N, Mavromati M, Migliaresi S, Barizzone N, Ruzickova S, Dostal C, Schmidt R E, Witte T, Papasteriades C, Kappou-Rigatou I, Endreffy E, Kovacs A, Ordi-Ros J, Balada E, Carreira P, Gomez-Reino J J, Gonzalez A

Abstract excerpt

Genetic variation in the interferon regulatory factor 5 (IRF5) gene affects systemic lupus erythematosus (SLE) susceptibility. However, association is complex and incompletely defined. We obtained fourteen European sample collections with a total of 1383 SLE patients and 1614 controls to better d...

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Source

Identifiers

PMID: 17568788
DOI: 10.1038/sj.gene.6364407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17568788-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Opposed independent effects and epistasis in the complex association of IRF5 to SLE.PMID 17568788Read ↗

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