Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes.

BMC medical genetics - 28 Nov 2007

Cooper Jason D, Smyth Deborah J, Bailey Rebecca, Payne Felicity, Downes Kate, Godfrey Lisa M, Masters Jennifer, Zeitels Lauren R, Vella Adrian, Walker Neil M, Todd John A

Abstract excerpt

BACKGROUND: As genes associated with immune-mediated diseases have an increased prior probability of being associated with other immune-mediated diseases, we tested three such genes, IL23R, IRF5 and CD40, for an association with type 1 diabetes. In addition, we tested seven genes, TAF5L, PDCD1, TCF7, IL12B, IL6, ICAM1 and TBX21, with published marginal or inconsistent evidence of an association with type 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Intercellular Adhesion Molecule-1

Share to Interleukin-6

Share to Programmed Cell Death 1 Receptor

Share to TATA-Binding Protein Associated Factors

Share to Transcription Factor TFIID

Source

Open in PubMed Open full text

Identifiers

PMID: 18045485
DOI: 10.1186/1471-2350-8-71
PMCID: PMC2217539

Genes

ICAM1
PDCD1
TCF7
TBX21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes.PMID 18045485Read ↗

Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.Semantic proximity Read ↗

Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.Semantic proximity Read ↗

Genetic factors affecting immune phenotypes in type 1 diabetesSemantic proximity Read ↗

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.Semantic proximity Read ↗

Functional evaluation of the type 1 diabetes (T1D) susceptibility candidate genes.Semantic proximity Read ↗

The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.Semantic proximity Read ↗

Genetic associations with diabetes: meta-analyses of 10 candidate polymorphisms.Semantic proximity Read ↗

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus.Semantic proximity Read ↗

Shared and distinct genetic variants in type 1 diabetes and celiac disease.Semantic proximity Read ↗

Genome-wide search for genes affecting the age at diagnosis of type 1 diabetes.Semantic proximity Read ↗

Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes.Semantic proximity Read ↗

Follow-up of 1715 SNPs from the Wellcome Trust Case Control Consortium genome-wide association study in type I diabetes families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.