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Article

Genetic association of IRF5 with SLE in Mexicans: higher frequency of the risk haplotype and its homozygozity than Europeans.

Human genetics - 1 Jul 2007

Reddy M V Prasad Linga, Velázquez-Cruz Rafael, Baca Vicente, Lima Guadalupe, Granados Julio, Orozco Lorena, Alarcón-Riquelme Marta E

Abstract excerpt

The IRF5 gene was found to be strongly associated with SLE. We identified two functional polymorphisms and recently an insertion/deletion together with a tag SNP defining the risk haplotype in individuals of European ancestry. We now analyzed sets of Mexican patients with SLE. Three polymorphisms in the IRF5 gene were genotyped in two sets of Mexican individuals with SLE and controls as well as in families...

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Source

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PMID: 17476532
DOI: 10.1007/s00439-007-0367-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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