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Article

Tissue-specific effects of the nuclear factor kappaB subunit p50 on myocardial ischemia-reperfusion injury.

The American journal of pathology - 1 Aug 2007

Frantz Stefan, Tillmanns Jochen, Kuhlencordt Peter J, Schmidt Isabel, Adamek Anna, Dienesch Charlotte, Thum Thomas, Gerondakis Steve, Ertl Georg, Bauersachs Johann

Abstract excerpt

Nuclear factor kappaB (NF-kappaB) is a ubiquitous transcription factor activated by various stimuli implicated in ischemia-reperfusion injury. However, the role of NF-kappaB in cardiac ischemia-reperfusion injury has not yet been well defined. Therefore, we investigated reperfusion damage in mice with targeted deletion of the NF-kappaB subunit p50. Electrophoretic mobility shift assays validated NF-kappaB...

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Identifiers

PMID: 17556593
DOI: 10.2353/ajpath.2007.061042
PMCID: PMC1934536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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