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Article

Expression of active alpha(1B)-adrenergic receptors in the heart does not alleviate ischemic reperfusion injury.

Journal of molecular and cellular cardiology - 1 Sept 2000

Gao X M, Wang B H, Woodcock E, Du X J

Abstract excerpt

Ischemic preconditioning reduces infarct size and improves cardiac function in various species, including mice. The mechanism for ischemic preconditioning protection is not entirely clear and activation of alpha(1B)-adrenergic receptors (AR) is believed to be involved. Transgenic mice expressing constitutively active mutant alpha(1B)-AR in the heart have enhanced alpha(1B)-AR activity and therefore can be used to...

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Identifiers

PMID: 10966830
DOI: 10.1006/jmcc.2000.1201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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