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Article

Gene deletion of NF-kappa B p50 does not alter the hepatic inflammatory response to ischemia/reperfusion.

Journal of hepatology - 1 Jul 2002

Kato Atsushi, Edwards Michael J, Lentsch Alex B

Abstract excerpt

BACKGROUND/AIMS: Nuclear factor kappa B (NF-kappa B) is a primary regulator of gene expression and is activated during hepatic ischemia/reperfusion injury. The objective of the present study was to determine whether activation of NF-kappa B is causally related to the induction of the acute inflammatory response induced by hepatic ischemia/reperfusion. METHODS: Wild-type (p50(+/+)) and NF-kappa B p50-deficient...

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Source

Identifiers

PMID: 12076861
DOI: 10.1016/s0168-8278(02)00068-5

Genes

MIP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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