Article
Cardiomyocyte-specific p65 NF-κB deletion protects the injured heart by preservation of calcium handling.
American journal of physiology. Heart and circulatory physiology - 1 Oct 2013
Zhang Xiu Q, Tang Ruhang, Li Ling, Szucsik Amanda, Javan Hadi, Saegusa Noriko, Spitzer Ken W, Selzman Craig H
Abstract excerpt
NF-κB is a well-known transcription factor that is intimately involved with inflammation and immunity. We have previously shown that NF-κB promotes inflammatory events and mediates adverse cardiac remodeling following ischemia reperfusion (I/R). Conversely, others have pointed to the beneficial i...
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