Article
Mutants in the Dictyostelium Arp2/3 complex and chemoattractant-induced actin polymerization.
Experimental cell research - 15 Jul 2007
Langridge Paul D, Kay Robert R
Abstract excerpt
We have investigated the role of the Arp2/3 complex in Dictyostelium cell chemotaxis towards cyclic-AMP and in the actin polymerization that is triggered by this chemoattractant. We confirm that the Arp2/3 complex is recruited to the cell perimeter, or into a pseudopod, after cyclic-AMP stimulation and that this is coincident with actin polymerization. This recruitment is inhibited when actin polymerization is...
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