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Article

Regulation of Dictyostelium morphogenesis by RapGAP3.

Developmental biology - 15 Apr 2009

Jeon Taeck J, Lee Susan, Weeks Gerald, Firtel Richard A

Abstract excerpt

Rap1 is a key regulator of cell adhesion and cell motility in Dictyostelium. Here, we identify a Rap1-specific GAP protein (RapGAP3) and provide evidence that Rap1 signaling regulates cell-cell adhesion and cell migration within the multicellular organism. RapGAP3 mediates the deactivation of Rap1 at the late mound stage of development and plays an important role in regulating cell sorting during apical tip...

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Identifiers

PMID: 19284976
DOI: 10.1016/j.ydbio.2009.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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