Article
Non-replication and inconsistency in the genome-wide association setting.
Human heredity - 1 Jan 2007
Ioannidis John P A
Abstract excerpt
Non-replication and inconsistency had been common features in the search for common variants of candidate genes affecting the risk of complex diseases. They may continue to require attention in the current era, when massive hypothesis-free testing of genetic variants is feasible. An empirical evaluation of the early experience with genome-wide association (GWA) studies suggests several examples where proposed...
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