Challenges in reproducibility of genetic association studies: lessons learned from the obesity field.

Abstract excerpt

A robust replication of initial genetic association findings has proved to be difficult in human complex diseases and more specifically in the obesity field. An obvious cause of non-replication in genetic association studies is the initial report of a false positive result, which can be explained by a non-heritable phenotype, insufficient sample size, improper correction for multiple testing, population...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epidemiologic Studies
• Share to False Positive Reactions
• Share to Genetic Association Studies